We have generated a novel monoclonal antibody targeting human FGFR1c (R1c mAb) that caused profound body weight and body fat loss in diet-induced obese mice due to decreased food intake (with energy expenditure unaltered), in turn improving glucose control.R1c mAb also caused weight loss in leptin-deficient ob/ob mice, leptin receptor-mutant db/db
Introduction and Purpose: Recently, depression has significantly marked its presence in both the scientific and social spheres due to its connections with suicides.According to WHO data, it affects approximately 280 million people and as much as 5% of all adults worldwide.The primary treatment for this condition includes drugs such as SSRIs and SNR
Ent-kaurene oxidase (EKO) catalyze three sequential oxidations in the early steps of gibberellin biosynthesis pathway.In this research, a cDNA sequence of InEKO1 gene in the model short-day plant Ipomoea nil was identified.Our studies revealed that inductive conditions for flowering caused an fender two tone amp increase in the transcriptional acti
Carcass parameters and meat quality in lambs that consumed diets having layer hen litter spitfire sapphires wheels (LL) were evaluated in a complete randomized study.Forty-two lambs were allocated equally (14 lambs/treatment diet) into one of three iso-nitrogenous diets for 75 days.To partially replace soybean meal and barley, LL was given at 0 (LL